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Search Results for " 3-hydroxy midostaurin "

4

Compounds

Cat No. Product Name Synonyms Targets
T12610L 3-Hydroxy Midostaurin CGP52421 FLT
3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM in culture medium and 9.8 μM in plasma. Though less selective, it ...
T19119 3-Hydroxy Midostaurin-D5 CGP52421-D5 Others
3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9....
T12791 (S)-3-Hydroxy Midostaurin (S)-CGP52421 Others
(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).
T12610 (R)-3-Hydroxy Midostaurin (R)-CGP52421 Others
(R)-3-Hydroxy Midostaurin is a potent inhibitor of kinases,is a major metabolite of midostaurin undergoing by the hepatic CYP3A4 enzyme,has the potential for acute myeloid leukemia (AML).
TargetMol